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MCB 4009: Structure and Function of Biological Macromolecules

Fundamentals of protein structure and the forces that stabilize structure. Topics include recurrent structural motifs, molecular ancestry/homology, evolution of protein structure, structure-function correlations, and the structural basis of regulation. Discussion of the techniques used to investigate structure, including X-ray diffraction, NMR, TEM, AFM, structure prediction, and computational simulations. Advanced topics may include chaperones, structural genomics and the roles of misfolded proteins in disease.

Credits
3
Offered
Spring 2027
Campuses
Storrs
Requirements
MCB 2000 or 3010, which may be taken concurrently, or instructor consent.
Plan MCB 4009 in HuskyScheduler

Spring 2027 sections

Taught by Andrei Alexandrescu.

SectionTypeMeetsInstructorCampusRoomSeats
001LEC12:30PM - 1:45PM / TuThAndrei AlexandrescuStorrsMCHU 1087 of 16 open

Seats as of Nov 12, 2026. HuskyScheduler shows live seats when you search.

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